Lineage for d4w5bb_ (4w5b B:)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2926589Fold d.3: Cysteine proteinases [54000] (1 superfamily)
    consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn
  4. 2926590Superfamily d.3.1: Cysteine proteinases [54001] (24 families) (S)
    the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet
  5. 2926591Family d.3.1.1: Papain-like [54002] (26 proteins)
  6. 2926815Protein Cruzain [54020] (1 species)
  7. 2926816Species Trypanosoma cruzi [TaxId:5693] [54021] (29 PDB entries)
  8. 2926859Domain d4w5bb_: 4w5b B: [269950]
    automated match to d3i06a_
    complexed with 3h5

Details for d4w5bb_

PDB Entry: 4w5b (more details), 2.7 Å

PDB Description: crystal structure analysis of cruzain with fragment 1 (n-(1h- benzimidazol-2-yl)-1,3-dimethyl-pyrazole-4-carboxamide)
PDB Compounds: (B:) Cruzipain

SCOPe Domain Sequences for d4w5bb_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4w5bb_ d.3.1.1 (B:) Cruzain {Trypanosoma cruzi [TaxId: 5693]}
apaavdwrargavtavkdqgqcgsswafsaignvecqwflaghpltnlseqmlvscdktd
sgcsgglmnnafewivqenngavytedsypyasgegisppcttsghtvgatitghvelpq
deaqiaawlavngpvavavdasswmtytggvmtscvseqldhgvllvgyndsaavpywii
knswttqwgeegyiriakgsnqclvkeeassavvg

SCOPe Domain Coordinates for d4w5bb_:

Click to download the PDB-style file with coordinates for d4w5bb_.
(The format of our PDB-style files is described here.)

Timeline for d4w5bb_: