SCOPe 2.05: Domain d4us2s_: 4us2 S:

Lineage for d4us2s_ (4us2 S:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.117: Ras GEF [48365] (1 superfamily)
   multihelical

4. Superfamily a.117.1: Ras GEF [48366] (1 family)

5. Family a.117.1.1: Ras GEF [48367] (2 proteins)

6. Protein automated matches [269917] (1 species)
   not a true protein

7. Species Homo sapiens [TaxId:9606] [269918] (9 PDB entries)

8. Domain d4us2s_: 4us2 S: [269935]
   Other proteins in same PDB: d4us2r_
   automated match to d1nvus_
   complexed with l7s

Details for d4us2s_

PDB Entry: 4us2, 2.48 Å

PDB Description: the crystal structure of h-ras and sos in complex with ligands

PDB Compounds: (S:) Son of sevenless homolog 1

SCOPe Domain Sequences for d4us2s_:

Sequence, based on SEQRES records:

>d4us2s_ a.117.1.1 (S:) automated matches {Homo sapiens [TaxId: 9606]}
qmrlpsadvyrfaepdseeniifeenmqpkagipiikagtviklierltyhmyadpnfvr
tflttyrsfckpqellsliierfeipepepteadriaiengdqplsaelkrfrkeyiqpv
qlrvlnvcrhwvehhfydferdayllqrmeefigtvrgkamkkwvesitkiiqrkkiard
ngpghnitfqsspptvewhisrpghietfdlltlhpieiarqltllesdlyravqpselv
gsvwtkedkeinspnllkmirhttnltlwfekcivetenleervavvsriieilqvfqel
nnfngvlevvsamnsspvyrldhtfeqipsrqkkileeahelsedhykkylaklrsinpp
cvpffgiyltnilkteegnpevlkrhgkelinfskrrkvaeitgeiqqyqnqpyclrves
dikrffenlnpmgnsmekeftdylfnksleieprnpkplprfpkkysyplkspgvrpsnp
r

Sequence, based on observed residues (ATOM records):

>d4us2s_ a.117.1.1 (S:) automated matches {Homo sapiens [TaxId: 9606]}
qmrlpsadvyrfaepdseeniifeenmqpkagipiikagtviklierltyhmyadpnfvr
tflttyrsfckpqellsliierfeipeplsaelkrfrkeyiqpvqlrvlnvcrhwvehhf
ydferdayllqrmeefigtvrgkamkkwvesitkiiqrkkiaqsspptvewhisrpghie
tfdlltlhpieiarqltllesdlyravqpselvgsvwtkedkeinspnllkmirhttnlt
lwfekcivetenleervavvsriieilqvfqelnnfngvlevvsamnsspvyrldhtfeq
ipsrqkkileeahelsedhykkylaklrsinppcvpffgiyltnilkteegnpevlkrhg
kelinfskrrkvaeitgeiqqyqnqpyclrvesdikrffenlnpmgnsmekeftdylfnk
sleieprnpkplprfpkkysyplkspgvrpsnpr

Timeline for d4us2s_:

• d4us2s_ is new in SCOPe 2.05-stable
  
• d4us2s_ appears in SCOPe 2.06
  
• d4us2s_ appears in the current release, SCOPe 2.08