SCOPe 2.05: Domain d4q91a_: 4q91 A:

Lineage for d4q91a_ (4q91 A:)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.42: beta-Trefoil [50352] (8 superfamilies)
   barrel, closed; n=6, S=12; and a hairpin triplet; meander
   duplication: has internal pseudo threefold symmetry

4. Superfamily b.42.1: Cytokine [50353] (3 families)

5. Family b.42.1.1: Fibroblast growth factors (FGF) [50354] (10 proteins)

6. Protein Acidic FGF (FGF1) [50357] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50359] (92 PDB entries)
   Uniprot P05230 16-152 ! Uniprot P05230

8. Domain d4q91a_: 4q91 A: [269780]
   automated match to d3ojma_
   complexed with fmt, po4; mutant

Details for d4q91a_

PDB Entry: 4q91, 1.8 Å

PDB Description: crystal structure of c16a/k12v/c117v/p134v mutant of human acidic fibroblast growth factor

PDB Compounds: (A:) fibroblast growth factor 1

SCOPe Domain Sequences for d4q91a_:

Sequence; same for both SEQRES and ATOM records:

>d4q91a_ b.42.1.1 (A:) Acidic FGF (FGF1) {Human (Homo sapiens) [TaxId: 9606]}
hhhhfnlppgnykkpvllyasngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgevyi
kstetgqylamdtdgllygsqtpneeclflerleenhyntyiskkhaeknwfvglkkngs
vkrgprthygqkailflvlpv

Timeline for d4q91a_:

• d4q91a_ is new in SCOPe 2.05-stable
  
• d4q91a_ is called d4q91a1 in SCOPe 2.06
  
• d4q91a_ appears in the current release, SCOPe 2.08, called d4q91a1