Lineage for d4pi3a_ (4pi3 A:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2497139Fold d.3: Cysteine proteinases [54000] (1 superfamily)
    consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn
  4. 2497140Superfamily d.3.1: Cysteine proteinases [54001] (24 families) (S)
    the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet
  5. 2497141Family d.3.1.1: Papain-like [54002] (26 protein domains)
  6. 2497357Protein Cruzain [54020] (1 species)
  7. 2497358Species Trypanosoma cruzi [TaxId:5693] [54021] (25 PDB entries)
  8. 2497366Domain d4pi3a_: 4pi3 A: [269749]
    automated match to d3i06a_
    complexed with 2v5

Details for d4pi3a_

PDB Entry: 4pi3 (more details), 1.27 Å

PDB Description: crystal structure analysis of cruzain bound to vinyl sulfone analog of wrr-483 (wrr-666)
PDB Compounds: (A:) Cruzipain

SCOPe Domain Sequences for d4pi3a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4pi3a_ d.3.1.1 (A:) Cruzain {Trypanosoma cruzi [TaxId: 5693]}

SCOPe Domain Coordinates for d4pi3a_:

Click to download the PDB-style file with coordinates for d4pi3a_.
(The format of our PDB-style files is described here.)

Timeline for d4pi3a_: