Lineage for d4nkca_ (4nkc A:)

  1. Root: SCOPe 2.07
  2. 2434694Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2434695Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2437818Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (2 families) (S)
  5. 2437819Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (16 proteins)
    Common fold covers whole protein structure
  6. 2437883Protein Aldose reductase (aldehyde reductase) [51436] (2 species)
  7. 2437884Species Human (Homo sapiens) [TaxId:9606] [51437] (155 PDB entries)
    Uniprot P15121
  8. 2437951Domain d4nkca_: 4nkc A: [269690]
    automated match to d1xgda_
    complexed with 2hz, nap

Details for d4nkca_

PDB Entry: 4nkc (more details), 1.12 Å

PDB Description: human aldose reductase complexed with schl7764 at 1.12 a
PDB Compounds: (A:) aldose reductase

SCOPe Domain Sequences for d4nkca_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4nkca_ c.1.7.1 (A:) Aldose reductase (aldehyde reductase) {Human (Homo sapiens) [TaxId: 9606]}
srillnngakmpilglgtwksppgqvteavkvaidvgyrhidcahvyqnenevgvaiqek
lreqvvkreelfivsklwctyhekglvkgacqktlsdlkldyldlylihwptgfkpgkef
fpldesgnvvpsdtnildtwaameelvdeglvkaigisnfnhlqvemilnkpglkykpav
nqiechpyltqekliqycqskgivvtaysplgspdrpwakpedpslledprikaiaakhn
kttaqvlirfpmqrnlvvipksvtperiaenfkvfdfelssqdmttllsynrnwrvcall
sctshkdypfheef

SCOPe Domain Coordinates for d4nkca_:

Click to download the PDB-style file with coordinates for d4nkca_.
(The format of our PDB-style files is described here.)

Timeline for d4nkca_: