SCOPe 2.08: Domain d5ajqb_: 5ajq B:

Lineage for d5ajqb_ (5ajq B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d5ajqb_: 5ajq B: [269632]
   automated match to d4aota_
   complexed with cl, db8, edo

Details for d5ajqb_

PDB Entry: 5ajq, 2.2 Å

PDB Description: human lok (stk10) in complex with bosutinib

PDB Compounds: (B:) serine/threonine-protein kinase 10

SCOPe Domain Sequences for d5ajqb_:

Sequence, based on SEQRES records:

>d5ajqb_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
hvrrdldpnevweivgelgdgafgkvykaknketgalaaakvietkseeeledyiveiei
latcdhpyivkllgayyhdgklwimiefcpggavdaimleldrgltepqiqvvcrqmlea
lnflhskriihrdlkagnvlmtlegdirladfgvsaknlktlqkrdsfigtpywmapevv
mcetmkdtpydykadiwslgitliemaqiepphhelnpmrvllkiaksdpptlltpskws
vefrdflkialdknpetrpsaaqllehpfvssitsnkalrelvaeaka

Sequence, based on observed residues (ATOM records):

>d5ajqb_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
hvrrdldpnevweivgelgdgafgkvykaknketgalaaakvledyiveieilatcdhpy
ivkllgayyhdgklwimiefcpggavdaimleldrgltepqiqvvcrqmlealnflhskr
iihrdlkagnvlmtlegdirladfgvsaktpywmapevvmcetmkdtpydykadiwslgi
tliemaqiepphhelnpmrvllkiaksdpptlltpskwsvefrdflkialdknpetrpsa
aqllehpfvssitsnkalrelvaeaka

Timeline for d5ajqb_:

• d5ajqb_ first appeared in SCOPe 2.05
  
• d5ajqb_ appears in SCOPe 2.07