Lineage for d1btka_ (1btk A:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2061576Fold b.55: PH domain-like barrel [50728] (2 superfamilies)
    barrel, partly opened; n*=6, S*=12; meander; capped by an alpha-helix
  4. 2061577Superfamily b.55.1: PH domain-like [50729] (14 families) (S)
  5. 2061578Family b.55.1.1: Pleckstrin-homology domain (PH domain) [50730] (48 protein domains)
    Pfam PF00169
  6. 2061598Protein Bruton's tyrosine kinase [50738] (1 species)
    contains Btk zinc-binding motif
  7. 2061599Species Human (Homo sapiens) [TaxId:9606] [50739] (3 PDB entries)
  8. 2061600Domain d1btka_: 1btk A: [26959]
    complexed with na, zn; mutant

Details for d1btka_

PDB Entry: 1btk (more details), 1.6 Å

PDB Description: ph domain and btk motif from bruton's tyrosine kinase mutant r28c
PDB Compounds: (A:) bruton's tyrosine kinase

SCOPe Domain Sequences for d1btka_:

Sequence, based on SEQRES records: (download)

>d1btka_ b.55.1.1 (A:) Bruton's tyrosine kinase {Human (Homo sapiens) [TaxId: 9606]}
aavilesiflkrsqqkkktsplnfkkclflltvhklsyyeydfergrrgskkgsidveki
tcvetvvpeknppperqiprrgeessemeqisiierfpypfqvvydegplyvfspteelr
krwihqlknvirynsdlvqkyhpcfwidgqylccsqtaknamgcqilen

Sequence, based on observed residues (ATOM records): (download)

>d1btka_ b.55.1.1 (A:) Bruton's tyrosine kinase {Human (Homo sapiens) [TaxId: 9606]}
aavilesiflkrsqqkkktsplnfkkclflltvhklsyyeydfergrrgskkgsidveki
tcvetvvpeknppperqimeqisiierfpypfqvvydegplyvfspteelrkrwihqlkn
virynsdlvqkyhpcfwidgqylccsqtaknamgcqilen

SCOPe Domain Coordinates for d1btka_:

Click to download the PDB-style file with coordinates for d1btka_.
(The format of our PDB-style files is described here.)

Timeline for d1btka_: