Lineage for d4wxia_ (4wxi A:)

  1. Root: SCOPe 2.07
  2. 2344607Class b: All beta proteins [48724] (178 folds)
  3. 2387558Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2387559Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2390288Family b.47.1.0: automated matches [191364] (1 protein)
    not a true family
  6. 2390289Protein automated matches [190438] (26 species)
    not a true protein
  7. 2390333Species Human (Homo sapiens) [TaxId:9606] [187421] (76 PDB entries)
  8. 2390384Domain d4wxia_: 4wxi A: [269539]
    automated match to d1p57b_
    complexed with 3vm, edo, so4

Details for d4wxia_

PDB Entry: 4wxi (more details), 2.6 Å

PDB Description: factor xia in complex with the inhibitor trans-n-{(1s)-1-[4-(3-amino-2h-indazol-6-yl)pyridin-2-yl]-2-phenylethyl}-4-(aminomethyl)cyclohexanecarboxamide
PDB Compounds: (A:) coagulation factor xi, light chain

SCOPe Domain Sequences for d4wxia_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4wxia_ b.47.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ivggtasvrgewpwqvtlhttsptqrhlcggsiignqwiltaahcfygvespkilrvysg
ilnqseikedtsffgvqeiiihdqykmaesgydiallklettvgygdsqrpiclpskgdr
nviytdcwvtgwgyrklrdkiqntlqkakiplvtneecqkryrghkithkmicagyregg
kdackgdsggplsckhnevwhlvgitswgegcaqrerpgvytnvveyvdwilektqav

SCOPe Domain Coordinates for d4wxia_:

Click to download the PDB-style file with coordinates for d4wxia_.
(The format of our PDB-style files is described here.)

Timeline for d4wxia_: