SCOPe 2.08: Domain d4s0ta_: 4s0t A:

Lineage for d4s0ta_ (4s0t A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Pregnane x receptor, PXR [63624] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [63625] (32 PDB entries)

8. Domain d4s0ta_: 4s0t A: [269371]
   Other proteins in same PDB: d4s0td_, d4s0te_
   automated match to d1m13a_
   complexed with 40u

Details for d4s0ta_

PDB Entry: 4s0t, 3.14 Å

PDB Description: structure of human pregnane x receptor ligand binding domain bound with adnectin-1 and compound-1

PDB Compounds: (A:) Nuclear receptor subfamily 1 group I member 2

SCOPe Domain Sequences for d4s0ta_:

Sequence, based on SEQRES records:

>d4s0ta_ a.123.1.1 (A:) Pregnane x receptor, PXR {Human (Homo sapiens) [TaxId: 9606]}
lteeqrmmirelmdaqmktfdttfshfknfrlpgvlssgcelpeslqapsreeaakwsqv
rkdlcslkvslqlrgedgsvwnykppadsggkeifsllphmadmstymfkgiisfakvis
yfrdlpiedqisllkgaafelcqlrfntvfnaetgtwecgrlsycledtaggfqqlllep
mlkfhymlkklqlheeeyvlmqaislfspdrpgvlqhrvvdqlqeqfaitlksyiecnrp
qpahrflflkimamltelrsinaqhtqrllriqdihpfatplmqelf

Sequence, based on observed residues (ATOM records):

>d4s0ta_ a.123.1.1 (A:) Pregnane x receptor, PXR {Human (Homo sapiens) [TaxId: 9606]}
lteeqrmmirelmdaqmktfdttfshfknfrlpgveslqapsreeaakwsqvrkdlcslk
vslqlrgedgsvwnykppadsggkeifsllphmadmstymfkgiisfakvisyfrdlpie
dqisllkgaafelcqlrfntvfnaetgtwecgrlsycledtaggfqqlllepmlkfhyml
kklqlheeeyvlmqaislfspdrpgvlqhrvvdqlqeqfaitlksyiecnrpqpahrflf
lkimamltelrsinaqhtqrllriqdihpfatplmqelf

Timeline for d4s0ta_:

• d4s0ta_ first appeared in SCOPe 2.05
  
• d4s0ta_ appears in SCOPe 2.07