Lineage for d4ryla_ (4ryl A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2129295Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest
  4. 2129296Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (60 families) (S)
  5. 2129455Family c.66.1.6: Arginine methyltransferase [53351] (4 protein domains)
    lacks the last two strands of the common fold replaced with a beta-sandwich oligomerisation subdomain
  6. 2129471Protein Protein arginine N-methyltransferase 3, PRMT3 [142581] (1 species)
  7. 2129472Species Human (Homo sapiens) [TaxId:9606] [142582] (5 PDB entries)
    Uniprot O60678 221-531
  8. 2129477Domain d4ryla_: 4ryl A: [269362]
    automated match to d2fyta1
    complexed with 3zg, unx

Details for d4ryla_

PDB Entry: 4ryl (more details), 2.1 Å

PDB Description: human protein arginine methyltransferase 3 in complex with 1- isoquinolin-6-yl-3-[2-oxo-2-(pyrrolidin-1-yl)ethyl]urea
PDB Compounds: (A:) PRMT3 protein

SCOPe Domain Sequences for d4ryla_:

Sequence, based on SEQRES records: (download)

>d4ryla_ c.66.1.6 (A:) Protein arginine N-methyltransferase 3, PRMT3 {Human (Homo sapiens) [TaxId: 9606]}
hygiheemlkdkirtesyrdfiyqnphifkdkvvldvgcgtgilsmfaakagakkvlgvd
qseilyqamdiirlnkledtitlikgkieevhlpvekvdviisewmgyfllfesmldsvl
yaknkylakggsvypdictislvavsdvnkhadriafwddvygfkmscmkkavipeavve
vldpktlisepcgikhidchttsisdlefssdftlkitrtsmctaiagyfdiyfeknchn
rvvfstgpqstkthwkqtvfllekpfsvkagealkgkvtvhknkkdprsltvtltlnnst
qtyglq

Sequence, based on observed residues (ATOM records): (download)

>d4ryla_ c.66.1.6 (A:) Protein arginine N-methyltransferase 3, PRMT3 {Human (Homo sapiens) [TaxId: 9606]}
hygiheemlkdkirtesyrdfiyqnphifkdkvvldvgcgtgilsmfaakagakkvlgvd
qseilyqamdiirlnkledtitlikgkieevhlpvekvdviisewmgyfllfesmldsvl
yaknkylakggsvypdictislvavsdvnkhadriafwddvygfkmscmkkavipeavve
vldpktlisepcgikhidchttsisdlefssdftlkitrtsmctaiagyfdiyfeknchn
rvvfstgpqstkthwkqtvfllekpfsvkagealkgkvtvhksltvtltlnnstqtyglq

SCOPe Domain Coordinates for d4ryla_:

Click to download the PDB-style file with coordinates for d4ryla_.
(The format of our PDB-style files is described here.)

Timeline for d4ryla_: