SCOP 1.71: Domain d1pfzd_: 1pfz D:

Lineage for d1pfzd_ (1pfz D:)

1. Root: SCOP 1.71

2. Class b: All beta proteins [48724] (149 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (2 families)

5. Family b.50.1.2: Pepsin-like [50646] (10 proteins)
   duplication: consists of two similar barrel domains
   N-terminal: barrel, partly opened; n*=6, S*=10

6. Protein Plasmepsin (a hemoglobin-degrading enzyme) [50673] (3 species)

7. Species Plasmodium falciparum, plasmepsin II [TaxId:5833] [50674] (8 PDB entries)

8. Domain d1pfzd_: 1pfz D: [26884]
   complexed with gol; mutant

Details for d1pfzd_

PDB Entry: 1pfz, 1.85 Å

PDB Description: proplasmepsin ii from plasmodium falciparum

SCOP Domain Sequences for d1pfzd_:

Sequence, based on SEQRES records:

>d1pfzd_ b.50.1.2 (D:) Plasmepsin (a hemoglobin-degrading enzyme) {Plasmodium falciparum, plasmepsin II}
hltigfkvenahdrilktikthklknyikesvnflnsgltktnylgssndnielvdfqni
mfygdaevgdnqqpftfildtgsanlwvpsvkcttagcltkhlydssksrtyekdgtkve
mnyvsgtvsgffskdlvtvgnlslpykfievidtngfeptytastfdgilglgwkdlsig
svdpivvelknqnkienalftfylpvhdkhtgfltiggieerfyegpltyeklnhdlywq
itldahvgnimlekancivdsgtsaitvptdflnkmlqnldvikvpflpfyvtlcnnskl
ptfeftsengkytlepeyylqhiedvgpglcmlniigldfpvptfilgdpfmrkyftvfd
ydnhsvgialakknl

Sequence, based on observed residues (ATOM records):

>d1pfzd_ b.50.1.2 (D:) Plasmepsin (a hemoglobin-degrading enzyme) {Plasmodium falciparum, plasmepsin II}
hltigfkvenahdrilktikthklknyikesvnflnsgltktnylgssndnielvdfqni
mfygdaevgdnqqpftfildtgsanlwvpsvkcttagcltkhlydssksrtyekdgtkve
mvsgffskdlvtvgnlslpykfievidtngfeptytastfdgilglgwkdlsigsvdpiv
velknqnkienalftfylpvhdkhtgfltiggieerfyegpltyeklnhdlywqitldah
vgnimlekancivdsgtsaitvptdflnkmlqnldvikvpflpfyvtlcnnsklptfeft
sengkytlepeyylqhiedvgpglcmlniigldfpvptfilgdpfmrkyftvfdydnhsv
gialakknl

Timeline for d1pfzd_:

• d1pfzd_ first appeared (with stable ids) in SCOP 1.55
  
• d1pfzd_ appears in SCOP 1.69
  
• d1pfzd_ appears in SCOP 1.73
  
• d1pfzd_ appears in the current release, SCOPe 2.08