SCOPe 2.01: Domain d1pfzc_: 1pfz C:

Lineage for d1pfzc_ (1pfz C:)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.2: Pepsin-like [50646] (11 proteins)
   duplication: consists of two similar barrel domains
   N-terminal: barrel, partly opened; n*=6, S*=10

6. Protein Plasmepsin (a hemoglobin-degrading enzyme) [50673] (3 species)

7. Species Plasmodium falciparum, plasmepsin II [TaxId:5833] [50674] (18 PDB entries)

8. Domain d1pfzc_: 1pfz C: [26883]
   complexed with gol

Details for d1pfzc_

PDB Entry: 1pfz, 1.85 Å

PDB Description: proplasmepsin ii from plasmodium falciparum

PDB Compounds: (C:) proplasmepsin II

SCOPe Domain Sequences for d1pfzc_:

Sequence, based on SEQRES records:

>d1pfzc_ b.50.1.2 (C:) Plasmepsin (a hemoglobin-degrading enzyme) {Plasmodium falciparum, plasmepsin II [TaxId: 5833]}
ehltigfkvenahdrilktikthklknyikesvnflnsgltktnylgssndnielvdfqn
imfygdaevgdnqqpftfildtgsanlwvpsvkcttagcltkhlydssksrtyekdgtkv
emnyvsgtvsgffskdlvtvgnlslpykfievidtngfeptytastfdgilglgwkdlsi
gsvdpivvelknqnkienalftfylpvhdkhtgfltiggieerfyegpltyeklnhdlyw
qitldahvgnimlekancivdsgtsaitvptdflnkmlqnldvikvpflpfyvtlcnnsk
lptfeftsengkytlepeyylqhiedvgpglcmlniigldfpvptfilgdpfmrkyftvf
dydnhsvgialakknl

Sequence, based on observed residues (ATOM records):

>d1pfzc_ b.50.1.2 (C:) Plasmepsin (a hemoglobin-degrading enzyme) {Plasmodium falciparum, plasmepsin II [TaxId: 5833]}
ehltigfkvenahdrilktikthklknyikesvnflnsgltvdfqnimfygdaevgdnqq
pftfildtgsanlwvpsvkcttagcltkhlydssksrtyekdgtkvemvsgffskdlvtv
gnlslpykfievidtngfeptytastfdgilglgwkdlsigsvdpivvelknqnkienal
ftfylpvhdkhtgfltiggieerfyegpltyeklnhdlywqitldahvgnimlekanciv
dsgtsaitvptdflnkmlqnldvikvpflpfyvtlcnnsklptfeftsengkytlepeyy
lqhiedvgpglcmlniigldfpvptfilgdpfmrkyftvfdydnhsvgialakknl

Timeline for d1pfzc_:

• d1pfzc_ first appeared (with stable ids) in SCOP 1.55
  
• d1pfzc_ appears in SCOP 1.75
  
• d1pfzc_ appears in SCOPe 2.02
  
• d1pfzc_ appears in the current release, SCOPe 2.08