SCOP 1.73: Domain d1bbsa_: 1bbs A:

Lineage for d1bbsa_ (1bbs A:)

1. Root: SCOP 1.73

2. Class b: All beta proteins [48724] (165 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (2 families)

5. Family b.50.1.2: Pepsin-like [50646] (10 proteins)
   duplication: consists of two similar barrel domains
   N-terminal: barrel, partly opened; n*=6, S*=10

6. Protein Chymosin (synonym: renin) [50667] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50669] (9 PDB entries)

8. Domain d1bbsa_: 1bbs A: [26877]

Details for d1bbsa_

PDB Entry: 1bbs, 2.8 Å

PDB Description: x-ray analyses of peptide inhibitor complexes define the structural basis of specificity for human and mouse renins

PDB Compounds: (A:) renin

SCOP Domain Sequences for d1bbsa_:

Sequence, based on SEQRES records:

>d1bbsa_ b.50.1.2 (A:) Chymosin (synonym: renin) {Human (Homo sapiens) [TaxId: 9606]}
ttssviltnymdtqyygeigigtppqtfkvvfdtgssnvwvpsskcsrlytacvyhklfd
asdsssykhngteltlrystgtvsgflsqdiitvggitvtqmfgevtempalpfmlaefd
gvvgmgfieqaigrvtpifdniisqgvlkedvfsfyynrdsensqslggqivlggsdpqh
yegnfhyinliktgvwqiqmkgvsvgsstllcedgclalvdtgasyisgstssieklmea
lgakkrlfdyvvkcnegptlpdisfhlggkeytltsadyvfqesysskklctlaihamdi
ppptgptwalgatfirkfytefdrrnnrigfalar

Sequence, based on observed residues (ATOM records):

>d1bbsa_ b.50.1.2 (A:) Chymosin (synonym: renin) {Human (Homo sapiens) [TaxId: 9606]}
ttssviltnymdtqyygeigigtppqtfkvvfdtgssnvwvpsskcsrlytacvyhklfd
asdsssykhngteltlrystgtvsgflsqdiitvggitvtqmfgevtempalpfmlaefd
gvvgmgfieqaigrvtpifdniisqgvlkedvfsfyynrdselggqivlggsdpqhyegn
fhyinliktgvwqiqmkgvsvgsstllcedgclalvdtgasyisgstssieklmealgak
krlfdyvvkcnegptlpdisfhlggkeytltsadyvfqesysskklctlaihamdipppt
gptwalgatfirkfytefdrrnnrigfalar

Timeline for d1bbsa_:

• d1bbsa_ first appeared (with stable ids) in SCOP 1.55, called d1bbs__
  
• d1bbsa_ was called d1bbs__ in SCOP 1.71
  
• d1bbsa_ appears in SCOP 1.75
  
• d1bbsa_ appears in the current release, SCOPe 2.08