SCOP 1.71: Domain d1bima_: 1bim A:

Lineage for d1bima_ (1bim A:)

1. Root: SCOP 1.71

2. Class b: All beta proteins [48724] (149 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (2 families)

5. Family b.50.1.2: Pepsin-like [50646] (10 proteins)
   duplication: consists of two similar barrel domains
   N-terminal: barrel, partly opened; n*=6, S*=10

6. Protein Chymosin (synonym: renin) [50667] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50669] (9 PDB entries)

8. Domain d1bima_: 1bim A: [26875]

Details for d1bima_

PDB Entry: 1bim, 2.8 Å

PDB Description: crystallographic studies on the binding modes of p2-p3 butanediamide renin inhibitors

SCOP Domain Sequences for d1bima_:

Sequence, based on SEQRES records:

>d1bima_ b.50.1.2 (A:) Chymosin (synonym: renin) {Human (Homo sapiens)}
gnttssviltnymdtqyygeigigtppqtfkvvfdtgssnvwvpsskcsrlytacvyhkl
fdasdsssykhngteltlrystgtvsgflsqdiitvggitvtqmfgevtempalpfmlae
fdgvvgmgfieqaigrvtpifdniisqgvlkedvfsfyynrdsensqslggqivlggsdp
qhyegnfhyinliktgvwqiqmkgvsvgsstllcedgclalvdtgasyisgstssieklm
ealgakkrlfdyvvkcnegptlpdisfhlggkeytltsadyvfqesysskklctlaiham
dippptgptwalgatfirkfytefdrrnnrigfalar

Sequence, based on observed residues (ATOM records):

>d1bima_ b.50.1.2 (A:) Chymosin (synonym: renin) {Human (Homo sapiens)}
gnttssviltnymdtqyygeigigtppqtfkvvfdtgssnvwvpsskcsrlytacvyhkl
fdasdsssykhngteltlrystgtvsgflsqdiitvggitvtqmfgevtempalpfmlae
fdgvvgmgfieqaigrvtpifdniisqgvlkedvfsfyynrdseslggqivlggsdpqhy
egnfhyinliktgvwqiqmkgvsvgsstllcedgclalvdtgasyisgstssieklmeal
gakkrlfdyvvkcnegptlpdisfhlggkeytltsadyvfqesysskklctlaihamdip
pptgptwalgatfirkfytefdrrnnrigfalar

Timeline for d1bima_:

• d1bima_ first appeared (with stable ids) in SCOP 1.55
  
• d1bima_ appears in SCOP 1.69
  
• d1bima_ appears in SCOP 1.73
  
• d1bima_ appears in the current release, SCOPe 2.08