SCOP 1.57: Domain d2ren__: 2ren -

Lineage for d2ren__ (2ren -)

1. Root: SCOP 1.57

2. Class b: All beta proteins [48724] (104 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)

4. Superfamily b.50.1: Acid proteases [50630] (2 families)

5. Family b.50.1.2: Pepsin-like [50646] (9 proteins)

6. Protein Chymosin (synonim: renin) [50667] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50669] (6 PDB entries)

8. Domain d2ren__: 2ren - [26874]

Details for d2ren__

PDB Entry: 2ren, 2.5 Å

PDB Description: structure of recombinant human renin, a target for cardiovascular- active drugs, at 2.5 angstroms resolution

SCOP Domain Sequences for d2ren__:

Sequence, based on SEQRES records:

>d2ren__ b.50.1.2 (-) Chymosin (synonim: renin) {Human (Homo sapiens)}
gnttssviltnymdtqyygeigigtppqtfkvvfdtgssnvwvpsskcsrlytacvyhkl
fdasdsssykhngteltlrystgtvsgflsqdiitvggitvtqmfgevtempalpfmlae
fdgvvgmgfieqaigrvtpifdniisqgvlkedvfsfyynrdsensqslggqivlggsdp
qhyegnfhyinliktgvwqiqmkgvsvgsstllcedgclalvdtgasyisgstssieklm
ealgakkrlfdyvvkcnegptlpdisfhlggkeytltsadyvfqesysskklctlaiham
dippptgptwalgatfirkfytefdrrnnrigfalar

Sequence, based on observed residues (ATOM records):

>d2ren__ b.50.1.2 (-) Chymosin (synonim: renin) {Human (Homo sapiens)}
gnttssviltnymdtqyygeigigtppqtfkvvfdtgssnvwvpsskcstacvyhklfda
sdsssykhngteltlrystgtvsgflsqdiitvggitvtqmfgevtempalpfmlaefdg
vvgmgfieqaigrvtpifdniisqgvlkedvfsfyynrdslggqivlggsdpqhyegnfh
yinliktgvwqiqmkgvsvgsstllcedgclalvdtgasyisgstssieklmealgakkr
lfdyvvkcnegptlpdisfhlggkeytltsadyvfctlaihamdippptgptwalgatfi
rkfytefdrrnnrigfalar

Timeline for d2ren__:

• d2ren__ first appeared (with stable ids) in SCOP 1.55
  
• d2ren__ appears in SCOP 1.59
  
• d2ren__ appears in the current release, SCOPe 2.08, called d2rena_