Lineage for d1lyb.2 (1lyb C:,D:)

  1. Root: SCOPe 2.05
  2. 1755445Class b: All beta proteins [48724] (176 folds)
  3. 1796116Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 1796117Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 1797457Family b.50.1.2: Pepsin-like [50646] (11 proteins)
    duplication: consists of two similar barrel domains
    N-terminal: barrel, partly opened; n*=6, S*=10
  6. 1797914Protein Cathepsin D [50665] (1 species)
  7. 1797915Species Human (Homo sapiens) [TaxId:9606] [50666] (3 PDB entries)
  8. 1797919Domain d1lyb.2: 1lyb C:,D: [26858]
    complexed with nag

Details for d1lyb.2

PDB Entry: 1lyb (more details), 2.5 Å

PDB Description: crystal structures of native and inhibited forms of human cathepsin d: implications for lysosomal targeting and drug design
PDB Compounds: (C:) cathepsin d, (D:) cathepsin d

SCOPe Domain Sequences for d1lyb.2:

Sequence; same for both SEQRES and ATOM records: (download)

>g1lyb.2 b.50.1.2 (C:,D:) Cathepsin D {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1lyb.2:

Click to download the PDB-style file with coordinates for d1lyb.2.
(The format of our PDB-style files is described here.)

Timeline for d1lyb.2: