Lineage for d1lyb.1 (1lyb A:,B:)

  1. Root: SCOPe 2.07
  2. 2344607Class b: All beta proteins [48724] (178 folds)
  3. 2391025Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 2391026Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 2392462Family b.50.1.2: Pepsin-like [50646] (11 protein domains)
    duplication: consists of two similar barrel domains
    N-terminal: barrel, partly opened; n*=6, S*=10
  6. 2392943Protein Cathepsin D [50665] (1 species)
  7. 2392944Species Human (Homo sapiens) [TaxId:9606] [50666] (3 PDB entries)
  8. 2392951Domain d1lyb.1: 1lyb A:,B: [26857]
    complexed with bma, man, nag

Details for d1lyb.1

PDB Entry: 1lyb (more details), 2.5 Å

PDB Description: crystal structures of native and inhibited forms of human cathepsin d: implications for lysosomal targeting and drug design
PDB Compounds: (A:) cathepsin d, (B:) cathepsin d

SCOPe Domain Sequences for d1lyb.1:

Sequence; same for both SEQRES and ATOM records: (download)

>g1lyb.1 b.50.1.2 (A:,B:) Cathepsin D {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1lyb.1:

Click to download the PDB-style file with coordinates for d1lyb.1.
(The format of our PDB-style files is described here.)

Timeline for d1lyb.1: