SCOP 1.59: Domain d1avf.2: 1avf Q:,J:

Lineage for d1avf.2 (1avf Q:,J:)

1. Root: SCOP 1.59

2. Class b: All beta proteins [48724] (110 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)

4. Superfamily b.50.1: Acid proteases [50630] (2 families)

5. Family b.50.1.2: Pepsin-like [50646] (9 proteins)

6. Protein Pepsin(ogen) [50658] (4 species)

7. Species Human (Homo sapiens), progastricsin (pepsinogen C) [TaxId:9606] [50661] (2 PDB entries)

8. Domain d1avf.2: 1avf Q:,J: [26854]

Details for d1avf.2

PDB Entry: 1avf, 2.36 Å

PDB Description: activation intermediate 2 of human gastricsin from human stomach

SCOP Domain Sequences for d1avf.2:

Sequence, based on SEQRES records:

>g1avf.2 b.50.1.2 (Q:,J:) Pepsin(ogen) {Human (Homo sapiens), progastricsin (pepsinogen C)}
avvkvplkkfksiretmkekglXvtyepmaymdaayfgeisigtppqnflvlfdtgssnl
wvpsvycqsqactshsrfnpsesstystngqtfslqygsgsltgffgydtltvqsiqvpn
qefglsenepgtnfvyaqfdgimglaypalsvdeattamqgmvqegaltspvfsvylsnq
qgssggavvfggvdsslytgqiywapvtqelywqigieefliggqasgwcsegcqaivdt
gtslltvpqqymsallqatgaqedeygqflvncnsiqnlpsltfiingvefplppssyil
snngyctvgveptylssqngqplwilgdvflrsyysvydlgnnrvgfataa

Sequence, based on observed residues (ATOM records):

>g1avf.2 b.50.1.2 (Q:,J:) Pepsin(ogen) {Human (Homo sapiens), progastricsin (pepsinogen C)}
avvkvplkkfksiretmkekglXvtyepmaymdaayfgeisigtppqnflvlfdtgssnl
wvpsvycqsqactshsrfnpsesstystngqtfslqygsgsltgffgydtltvqsiqvpn
qefglsenepgtnfvyaqfdgimglaypalsvdeattamqgmvqegaltspvfsvylsng
gavvfggvdsslytgqiywapvtqelywqigieefliggqasgwcsegcqaivdtgtsll
tvpqqymsallqatgaqedeygqflvncnsiqnlpsltfiingvefplppssyilsnngy
ctvgveptylssqngqplwilgdvflrsyysvydlgnnrvgfataa

Timeline for d1avf.2:

• d1avf.2 first appeared (with stable ids) in SCOP 1.55
  
• d1avf.2 appears in SCOP 1.57
  
• d1avf.2 appears in SCOP 1.61
  
• d1avf.2 appears in the current release, SCOPe 2.08