SCOPe 2.08: Domain d1htr.1: 1htr P:,B:

Lineage for d1htr.1 (1htr P:,B:)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.2: Pepsin-like [50646] (11 proteins)
   duplication: consists of two similar barrel domains
   N-terminal: barrel, partly opened; n*=6, S*=10

6. Protein Pepsin(ogen) [50658] (4 species)

7. Species Human (Homo sapiens), progastricsin (pepsinogen C) [TaxId:9606] [50661] (2 PDB entries)

8. Domain d1htr.1: 1htr P:,B: [26852]

Details for d1htr.1

PDB Entry: 1htr, 1.62 Å

PDB Description: crystal and molecular structures of human progastricsin at 1.62 angstroms resolution

PDB Compounds: (B:) gastricsin, (P:) progastricsin (pro segment)

SCOPe Domain Sequences for d1htr.1:

Sequence; same for both SEQRES and ATOM records:

>g1htr.1 b.50.1.2 (P:,B:) Pepsin(ogen) {Human (Homo sapiens), progastricsin (pepsinogen C) [TaxId: 9606]}
avvkvplkkfksiretmkekgllgeflrthkydpawkyrfgdlXsvtyepmaymdaayfg
eisigtppqnflvlfdtgssnlwvpsvycqsqactshsrfnpsesstystngqtfslqyg
sgsltgffgydtltvqsiqvpnqefglsenepgtnfvyaqfdgimglaypalsvdeatta
mqgmvqegaltspvfsvylsnqqgssggavvfggvdsslytgqiywapvtqelywqigie
efliggqasgwcsegcqaivdtgtslltvpqqymsallqatgaqedeygqflvncnsiqn
lpsltfiingvefplppssyilsnngyctvgveptylssqngqplwilgdvflrsyysvy
dlgnnrvgfataa

Timeline for d1htr.1:

• d1htr.1 first appeared (with stable ids) in SCOP 1.55
  
• d1htr.1 appears in SCOPe 2.07