SCOPe 2.08: Domain d4o7ua_: 4o7u A:

Lineage for d4o7ua_ (4o7u A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families)
   automatically mapped to Pfam PF00303

5. Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins)

6. Protein automated matches [190469] (17 species)
   not a true protein

7. Species Enterococcus faecalis [TaxId:1351] [194752] (5 PDB entries)

8. Domain d4o7ua_: 4o7u A: [268461]
   automated match to d3uwlb_
   complexed with edo, so4, ss7, thf

Details for d4o7ua_

PDB Entry: 4o7u, 2.4 Å

PDB Description: etherocomplex of enteroccocus faecalis thymidylate synthase with 5- hydroxymethilene-6-hydrofolic acid and the phtalimidic inhibitor ss7

PDB Compounds: (A:) Thymidylate synthase

SCOPe Domain Sequences for d4o7ua_:

Sequence, based on SEQRES records:

>d4o7ua_ d.117.1.1 (A:) automated matches {Enterococcus faecalis [TaxId: 1351]}
meeaylalgkkileeghfkedrtgtgtyslfgyqmrfdlakgfpllttkrvpfgliksel
lwflkgdtniryllernnhiwdewaferyvksadyqgpdmtdfghrvlqdpafaeqykee
hqkfcdailndaefaekygelgniygaqwrhwetkdgsfidqlanviemiktnpdsrrli
vsawnpedvpsmalppchtmfqfyvnegklscqlyqrsadvflgvpfniasyallthlia
hetglevgefvhtlgdahlyqnhveqmqeqlsrevrsfptlvlnpdkasvfdfdmedikv
egydphptikapi

Sequence, based on observed residues (ATOM records):

>d4o7ua_ d.117.1.1 (A:) automated matches {Enterococcus faecalis [TaxId: 1351]}
meeaylalgkkileeghfkedrtgtgtyslfgyqmrfdlakgfpllttkrvpfgliksel
lwflkgdtniryllernnhiwdewaferyvksadyqykeehqkfcdailndaefaekyge
lgniygaqwrhwetkdgsfidqlanviemiktnpdsrrlivsawnpedvpsmalppchtm
fqfyvnegklscqlyqrsadvflgvpfniasyallthliahetglevgefvhtlgdahly
qnhveqmqeqlsrevrsfptlvlnpsvfdfdmedikvegydphptikapi

Timeline for d4o7ua_:

• d4o7ua_ first appeared in SCOPe 2.05
  
• d4o7ua_ appears in SCOPe 2.07