SCOPe 2.05: Domain d4ns3e_: 4ns3 E:

Lineage for d4ns3e_ (4ns3 E:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.82: ALDH-like [53719] (1 superfamily)
   consists of two similar domains with 3 layers (a/b/a) each; duplication
   core: parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.82.1: ALDH-like [53720] (3 families)
   binds NAD differently from other NAD(P)-dependent oxidoreductases

5. Family c.82.1.0: automated matches [191448] (1 protein)
   not a true family

6. Protein automated matches [190683] (38 species)
   not a true protein

7. Species Mycobacterium tuberculosis [TaxId:83332] [225379] (7 PDB entries)

8. Domain d4ns3e_: 4ns3 E: [268413]
   automated match to d4idma_
   complexed with b12, nad

Details for d4ns3e_

PDB Entry: 4ns3, 2.38 Å

PDB Description: crystal structure of the delta-pyrroline-5-carboxylate dehydrogenase from mycobacterium tuberculosis bound with nad and cobalamin

PDB Compounds: (E:) Delta-1-pyrroline-5-carboxylate dehydrogenase

SCOPe Domain Sequences for d4ns3e_:

Sequence, based on SEQRES records:

>d4ns3e_ c.82.1.0 (E:) automated matches {Mycobacterium tuberculosis [TaxId: 83332]}
hmdaitqvpvpanepvhdyapkspertrlrtelasladhpidlphviggrhrmgdgerid
vvqphrhaarlgtltnathadaaaaveaamsaksdwaalpfderaavflraadllagpwr
ekiaaatmlgqsksvyqaeidavcelidfwrfnvafarqileqqpisgpgewnridyrpl
dgfvyaitpfnftsiagnlptapalmgntviwkpsitqtlaayltmqlleaaglppgvin
lvtgdgfavsdvaladprlagihftgstatfghlwqwvgtnigryhsyprlvgetggkdf
vvahasarpdvlrtalirgafdyqgqkcsavsrafiahsvwqrmgdellakaaelrygdi
tdlsnyggalidqrafvknvdaierakgaaavtvavggeyddsegyfvrptvllsddptd
esfvieyfgpllsvhvypderyeqildvidtgsryaltgaviaddrqavltaldrlrfaa
gnfyvndkptgavvgrqpfggargsdtndkagsplnllrwtsarsiketfvaatdhiyph
mav

Sequence, based on observed residues (ATOM records):

>d4ns3e_ c.82.1.0 (E:) automated matches {Mycobacterium tuberculosis [TaxId: 83332]}
hmdaitqvpvpanepvhdyapkspertrlrtelasladhpidlphviggrhrmgdgerid
vvqphrhaarlgtltnathadaaaaveaamsaksdwaalpfderaavflraadllagpwr
ekiaaatmlgqsksvyqaeidavcelidfwrfnvafarqileqqpisgpgewnridyrpl
dgfvyaitpfnftsiagnlptapalmgntviwkpsitqtlaayltmqlleaaglppgvin
lvtgdgfavsdvaladprlagihftgstatfghlwqwvgtnigryhsyprlvgetggkdf
vvahasarpdvlrtalirgafdyqgqkcsavsrafiahsvwqrmgdellakaaelrygdi
tdlsnyggalidqrafvknvdaierakgaaavtvavggeyddsegyfvrptvllsddpyf
gpllsvhvypderyeqildvidtgyaltgaviaddrqavltaldrlrfaagnfyvndkpt
avvgrqpfggargsdtndkagsplnllrwtsarsiketfvaatdhiyphmav

Timeline for d4ns3e_:

• d4ns3e_ is new in SCOPe 2.05-stable
  
• d4ns3e_ is called d4ns3e1 in SCOPe 2.06
  
• d4ns3e_ appears in the current release, SCOPe 2.08, called d4ns3e1