SCOPe 2.08: Domain d4ns3f1: 4ns3 F:1-541

Lineage for d4ns3f1 (4ns3 F:1-541)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.82: ALDH-like [53719] (1 superfamily)
   consists of two similar domains with 3 layers (a/b/a) each; duplication
   core: parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.82.1: ALDH-like [53720] (3 families)
   binds NAD differently from other NAD(P)-dependent oxidoreductases

5. Family c.82.1.0: automated matches [191448] (1 protein)
   not a true family

6. Protein automated matches [190683] (61 species)
   not a true protein

7. Species Mycobacterium tuberculosis [TaxId:83332] [225379] (7 PDB entries)

8. Domain d4ns3f1: 4ns3 F:1-541 [268409]
   Other proteins in same PDB: d4ns3a2, d4ns3b2, d4ns3c2, d4ns3d2, d4ns3e2, d4ns3f2
   automated match to d4idma_
   complexed with b12, nad

Details for d4ns3f1

PDB Entry: 4ns3, 2.38 Å

PDB Description: crystal structure of the delta-pyrroline-5-carboxylate dehydrogenase from mycobacterium tuberculosis bound with nad and cobalamin

PDB Compounds: (F:) Delta-1-pyrroline-5-carboxylate dehydrogenase

SCOPe Domain Sequences for d4ns3f1:

Sequence, based on SEQRES records:

>d4ns3f1 c.82.1.0 (F:1-541) automated matches {Mycobacterium tuberculosis [TaxId: 83332]}
mdaitqvpvpanepvhdyapkspertrlrtelasladhpidlphviggrhrmgdgeridv
vqphrhaarlgtltnathadaaaaveaamsaksdwaalpfderaavflraadllagpwre
kiaaatmlgqsksvyqaeidavcelidfwrfnvafarqileqqpisgpgewnridyrpld
gfvyaitpfnftsiagnlptapalmgntviwkpsitqtlaayltmqlleaaglppgvinl
vtgdgfavsdvaladprlagihftgstatfghlwqwvgtnigryhsyprlvgetggkdfv
vahasarpdvlrtalirgafdyqgqkcsavsrafiahsvwqrmgdellakaaelrygdit
dlsnyggalidqrafvknvdaierakgaaavtvavggeyddsegyfvrptvllsddptde
sfvieyfgpllsvhvypderyeqildvidtgsryaltgaviaddrqavltaldrlrfaag
nfyvndkptgavvgrqpfggargsdtndkagsplnllrwtsarsiketfvaatdhiyphm
a

Sequence, based on observed residues (ATOM records):

>d4ns3f1 c.82.1.0 (F:1-541) automated matches {Mycobacterium tuberculosis [TaxId: 83332]}
mdaitqvpvpanepvhdyapkspertrlrtelasladhpidlphviggrhrmgdgeridv
vqphrhaarlgtltnathadaaaaveaamsaksdwaalpfderaavflraadllagpwre
kiaaatmlgqsksvyqaeidavcelidfwrfnvafarqileqqpisgpgewnridyrpld
gfvyaitpfnftsiagnlptapalmgntviwkpsitqtlaayltmqlleaaglppgvinl
vtgdgfavsdvaladprlagihftgstatfghlwqwvgtnigryhsyprlvgetggkdfv
vahasarpdvlrtalirgafdyqgqkcsavsrafiahsvwqrmgdellakaaelrygdit
dlsnyggalidqrafvknvdaierakgaaavtvavggeyddsegyfvrptvllsddpeyf
gpllsvhvypderyeqildvidtgsryaltgaviaddrqavltaldrlrfaagnfyvndk
ptgavvgrqpfggargsdtndkagsplnllrwtsarsiketfvaatdhiyphma

Timeline for d4ns3f1:

• d4ns3f1 first appeared in SCOPe 2.05, called d4ns3f_
  
• d4ns3f1 appears in SCOPe 2.07