Lineage for d4clea_ (4cle A:)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2426096Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2426097Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2430344Family c.2.1.0: automated matches [191313] (1 protein)
    not a true family
  6. 2430345Protein automated matches [190069] (249 species)
    not a true protein
  7. 2432609Species Trypanosoma brucei [TaxId:5702] [226801] (37 PDB entries)
  8. 2432666Domain d4clea_: 4cle A: [268165]
    automated match to d4kwib_
    complexed with dtd, jr2, nap

Details for d4clea_

PDB Entry: 4cle (more details), 1.8 Å

PDB Description: Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor and inhibitor
PDB Compounds: (A:) pteridine reductase 1

SCOPe Domain Sequences for d4clea_:

Sequence, based on SEQRES records: (download)

>d4clea_ c.2.1.0 (A:) automated matches {Trypanosoma brucei [TaxId: 5702]}
eapaavvtgaakrigraiavklhqtgyrvvihyhnsaeaavsladelnkersntavvcqa
dltnsnvlpasceeiinscfrafgrcdvlvnnasafyptplvqgdhednsngktvetqva
eligtnaiapflltmsfaqrqkgtnpnctssnlsivnlcdamvdqpcmafslynmgkhal
vgltqsaalelapygirvngvapgvsllpvamgeeekdkwrrkvplgrreasaeqiadav
iflvsgsaqyitgsiikvdgglslvha

Sequence, based on observed residues (ATOM records): (download)

>d4clea_ c.2.1.0 (A:) automated matches {Trypanosoma brucei [TaxId: 5702]}
eapaavvtgaakrigraiavklhqtgyrvvihyhnsaeaavsladelnkersntavvcqa
dltnsnvlpasceeiinscfrafgrcdvlvnnasafyptplvqgktvetqvaeligtnai
apflltmsfaqrqkssnlsivnlcdamvdqpcmafslynmgkhalvgltqsaalelapyg
irvngvapgvsllpvamgeeekdkwrrkvplgrreasaeqiadaviflvsgsaqyitgsi
ikvdgglslvha

SCOPe Domain Coordinates for d4clea_:

Click to download the PDB-style file with coordinates for d4clea_.
(The format of our PDB-style files is described here.)

Timeline for d4clea_: