Lineage for d1hsia_ (1hsi A:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2058814Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 2058815Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 2058816Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 protein domains)
    dimer of identical mono-domain chains, each containing (6,10) barrel
  6. 2059984Protein Human immunodeficiency virus type 2 (HIV-2) protease [50634] (2 species)
  7. 2059992Species Human immunodeficiency virus type 2 [TaxId:11709] [50635] (15 PDB entries)
  8. 2060015Domain d1hsia_: 1hsi A: [26737]

Details for d1hsia_

PDB Entry: 1hsi (more details), 2.5 Å

PDB Description: crystal structure at 1.9 angstroms resolution of human immunodeficiency virus (hiv) ii protease complexed with l-735,524, an orally bioavailable inhibitor of the hiv proteases
PDB Compounds: (A:) hiv-2 protease

SCOPe Domain Sequences for d1hsia_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1hsia_ b.50.1.1 (A:) Human immunodeficiency virus type 2 (HIV-2) protease {Human immunodeficiency virus type 2 [TaxId: 11709]}

SCOPe Domain Coordinates for d1hsia_:

Click to download the PDB-style file with coordinates for d1hsia_.
(The format of our PDB-style files is described here.)

Timeline for d1hsia_:

View in 3D
Domains from other chains:
(mouse over for more information)