Lineage for d4qsmg1 (4qsm G:2-160)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2090218Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2090219Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2093044Family c.2.1.5: LDH N-terminal domain-like [51848] (9 protein domains)
  6. 2093083Protein Lactate dehydrogenase [51859] (18 species)
  7. 2093144Species Human (Homo sapiens), muscle isoform (M chain) [TaxId:9606] [63940] (16 PDB entries)
  8. 2093203Domain d4qsmg1: 4qsm G:2-160 [267361]
    Other proteins in same PDB: d4qsma2, d4qsma3, d4qsmb2, d4qsmc2, d4qsmc3, d4qsmd2, d4qsmd3, d4qsme2, d4qsmf2, d4qsmg2, d4qsmh2
    automated match to d4l4ra1
    complexed with 38k

Details for d4qsmg1

PDB Entry: 4qsm (more details), 3 Å

PDB Description: Crystal structure of human muscle L-lactate dehydrogenase in complex with inhibitor 2, 3-{[7-(2,4-dimethoxypyrimidin-5-yl)-3-sulfamoylquinolin-4-yl]amino}benzoic acid
PDB Compounds: (G:) L-lactate dehydrogenase A chain

SCOPe Domain Sequences for d4qsmg1:

Sequence; same for both SEQRES and ATOM records: (download)

>d4qsmg1 c.2.1.5 (G:2-160) Lactate dehydrogenase {Human (Homo sapiens), muscle isoform (M chain) [TaxId: 9606]}

SCOPe Domain Coordinates for d4qsmg1:

Click to download the PDB-style file with coordinates for d4qsmg1.
(The format of our PDB-style files is described here.)

Timeline for d4qsmg1: