Lineage for d4qsmc2 (4qsm C:161-333)

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1938734Fold d.162: LDH C-terminal domain-like [56326] (1 superfamily)
    unusual fold, defines family
  4. 1938735Superfamily d.162.1: LDH C-terminal domain-like [56327] (3 families) (S)
  5. 1938736Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain [56328] (5 proteins)
    N-terminal domain is NAD-binding module (alpha/beta Rossmann-fold domain)
    automatically mapped to Pfam PF02866
  6. 1938743Protein Lactate dehydrogenase [56339] (18 species)
  7. 1938797Species Human (Homo sapiens), muscle isoform (M chain) [TaxId:9606] [64445] (13 PDB entries)
  8. 1938852Domain d4qsmc2: 4qsm C:161-333 [267354]
    Other proteins in same PDB: d4qsma1, d4qsmb1, d4qsmc1, d4qsmd1, d4qsme1, d4qsmf1, d4qsmg1, d4qsmh1
    automated match to d4l4ra2
    complexed with 38k

Details for d4qsmc2

PDB Entry: 4qsm (more details), 3 Å

PDB Description: crystal structure of human muscle l-lactate dehydrogenase in complex with inhibitor 2, 3-{[7-(2,4-dimethoxypyrimidin-5-yl)-3- sulfamoylquinolin-4-yl]amino}benzoic acid
PDB Compounds: (C:) L-lactate dehydrogenase A chain

SCOPe Domain Sequences for d4qsmc2:

Sequence; same for both SEQRES and ATOM records: (download)

>d4qsmc2 d.162.1.1 (C:161-333) Lactate dehydrogenase {Human (Homo sapiens), muscle isoform (M chain) [TaxId: 9606]}

SCOPe Domain Coordinates for d4qsmc2:

Click to download the PDB-style file with coordinates for d4qsmc2.
(The format of our PDB-style files is described here.)

Timeline for d4qsmc2: