SCOPe 2.07: Domain d2upjb_: 2upj B:

Lineage for d2upjb_ (2upj B:)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (9 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (578 PDB entries)
   Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167

8. Domain d2upjb_: 2upj B: [26697]
   complexed with u02

Details for d2upjb_

PDB Entry: 2upj, 3 Å

PDB Description: hiv-1 protease complex with u100313 ([3-[[3-[cyclopropyl [4-hydroxy-2oxo-6-[1-(phenylmethyl)propyl]-2h-pyran-3-yl] methyl]phenyl]amino]-3-oxo-propyl]carbamic acid tert-butyl ester)

PDB Compounds: (B:) hiv-1 protease

SCOPe Domain Sequences for d2upjb_:

Sequence; same for both SEQRES and ATOM records:

>d2upjb_ b.50.1.1 (B:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf

Timeline for d2upjb_:

• d2upjb_ first appeared (with stable ids) in SCOP 1.55
  
• d2upjb_ appears in SCOPe 2.06
  
• d2upjb_ appears in the current release, SCOPe 2.08