SCOPe 2.08: Domain d4nm7a1: 4nm7 A:25-383

Lineage for d4nm7a1 (4nm7 A:25-383)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d4nm7a1: 4nm7 A:25-383 [266946]
   Other proteins in same PDB: d4nm7a2
   automated match to d1j1bb_
   complexed with adp, cl, dtt, gol, mg

Details for d4nm7a1

PDB Entry: 4nm7, 2.3 Å

PDB Description: Crystal structure of GSK-3/Axin complex bound to phosphorylated Wnt receptor LRP6 e-motif

PDB Compounds: (A:) GSK3B protein

SCOPe Domain Sequences for d4nm7a1:

Sequence, based on SEQRES records:

>d4nm7a1 d.144.1.7 (A:25-383) automated matches {Human (Homo sapiens) [TaxId: 9606]}
smkvsrdkdgskvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvai
kkvlqdkrfknrelqimrkldhcnivrlryffyssgekkdevylnlvldyvpetvyrvar
hysrakqtlpviyvklymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsa
kqlvrgepnvsyicsryyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgvd
qlveiikvlgtptreqiremnpnytefkfpqikahpwtkvfrprtppeaialcsrlleyt
ptarltpleacahsffdelrdpnvklpngrdtpalfnfttqelssnpplatilipphar

Sequence, based on observed residues (ATOM records):

>d4nm7a1 d.144.1.7 (A:25-383) automated matches {Human (Homo sapiens) [TaxId: 9606]}
smkvsrdskvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaikkv
lqdkrfknrelqimrkldhcnivrlryffysskkdevylnlvldyvpetvyrvarhysra
kqtlpviyvklymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsakqlvr
gepnvsyicsryyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdqlvei
ikvlgtptreqiremnpnytefkfpqikahpwtkvfrprtppeaialcsrlleytptarl
tpleacahsffdelrdpnvklpngrdtpalfnfttqelssnpplatilipphar

Timeline for d4nm7a1:

• d4nm7a1 first appeared in SCOPe 2.05, called d4nm7a_
  
• d4nm7a1 appears in SCOPe 2.07