SCOP 1.63: Domain d1d4sa_: 1d4s A:

Lineage for d1d4sa_ (1d4s A:)

1. Root: SCOP 1.63

2. Class b: All beta proteins [48724] (119 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (2 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (8 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (1 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (151 PDB entries)

8. Domain d1d4sa_: 1d4s A: [26692]

Details for d1d4sa_

PDB Entry: 1d4s, 2.5 Å

PDB Description: hiv-1 protease v82f/i84v double mutant/tipranavir complex

SCOP Domain Sequences for d1d4sa_:

Sequence; same for both SEQRES and ATOM records:

>d1d4sa_ b.50.1.1 (A:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1}
pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpfnvigrnlltqigctlnf

Timeline for d1d4sa_:

• d1d4sa_ first appeared (with stable ids) in SCOP 1.55
  
• d1d4sa_ appears in SCOP 1.61
  
• d1d4sa_ appears in SCOP 1.65
  
• d1d4sa_ appears in the current release, SCOPe 2.08