SCOPe 2.08: Domain d4mw5b2: 4mw5 B:237-606

Lineage for d4mw5b2 (4mw5 B:237-606)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.26: Adenine nucleotide alpha hydrolase-like [52373] (3 superfamilies)
   core: 3 layers, a/b/a ; parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.26.1: Nucleotidylyl transferase [52374] (6 families)

5. Family c.26.1.0: automated matches [191377] (1 protein)
   not a true family

6. Protein automated matches [190459] (61 species)
   not a true protein

7. Species Trypanosome (Trypanosoma brucei) [TaxId:5691] [188998] (16 PDB entries)

8. Domain d4mw5b2: 4mw5 B:237-606 [266808]
   Other proteins in same PDB: d4mw5a2, d4mw5b1, d4mw5b3
   automated match to d1rqga2
   protein/RNA complex; complexed with 415, dms, gol, met, so4

Details for d4mw5b2

PDB Entry: 4mw5, 2.35 Å

PDB Description: Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(3-chloro-5-methoxybenzyl)amino]propyl}-3-phenylurea (Chem 1415)

PDB Compounds: (B:) Methionyl-tRNA synthetase

SCOPe Domain Sequences for d4mw5b2:

Sequence, based on SEQRES records:

>d4mw5b2 c.26.1.0 (B:237-606) automated matches {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
kvekvffvtspiyyvnaaphighvystlitdvigryhrvkgervfaltgtdehgqkvaea
akqkqvspydfttavagefkkcfeqmdysidyfirttneqhkavvkelwtkleqkgdiyl
gryegwysisdesfltpqnitdgvdkdgnpckvslesghvvtwvseenymfrlsafrerl
lewyhanpgcivpefrrreviravekglpdlsvsraratlhnwaipvpgnpdhcvyvwld
altnyltgsrlrvdesgkevslvddfnelerfpadvhvigkdilkfhaiywpafllsagl
plpkkivahgwwtkdrkkiskslgnvfdpvekaeefgydalkyfllresgfsddgdysdk
nmiarlngel

Sequence, based on observed residues (ATOM records):

>d4mw5b2 c.26.1.0 (B:237-606) automated matches {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
kvekvffvtspiyyvnaaphighvystlitdvigryhrvkgervfaltgtdehgqkvaea
akqkqvspydfttavagefkkcfeqmdysidyfirttneqhkavvkelwtkleqkgdiyl
gryegwysisdesfltpqnitdgvdkvslesghvvtwvseenymfrlsafrerllewyha
npgcivpefrrreviravekglpdlsvsraratlhnwaipvpgnpdhcvyvwldaltnyl
tgsrlrvdesgkevslvddfnelerfpadvhvigkdilkfhaiywpafllsaglplpkki
vahgwwtkdrkkiskslgnvfdpvekaeefgydalkyfllresgfsddgdysdknmiarl
ngel

Timeline for d4mw5b2:

• d4mw5b2 first appeared in SCOPe 2.05
  
• d4mw5b2 appears in SCOPe 2.07