Lineage for d1hege_ (1heg E:)

  1. Root: SCOP 1.71
  2. 546417Class b: All beta proteins [48724] (149 folds)
  3. 562942Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 562943Superfamily b.50.1: Acid proteases [50630] (2 families) (S)
  5. 562944Family b.50.1.1: Retroviral protease (retropepsin) [50631] (8 proteins)
    dimer of identical mono-domain chains, each containing (6,10) barrel
  6. 562960Protein Human immunodeficiency virus type 1 protease [50632] (1 species)
  7. 562961Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (179 PDB entries)
  8. 563243Domain d1hege_: 1heg E: [26664]
    complexed with ohe, ome

Details for d1hege_

PDB Entry: 1heg (more details), 2.2 Å

PDB Description: the crystal structures at 2.2 angstroms resolution of hydroxyethylene- based inhibitors bound to human immunodeficiency virus type 1 protease show that the inhibitors are present in two distinct orientations

SCOP Domain Sequences for d1hege_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1hege_ b.50.1.1 (E:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1}
pqitlwqrplvtikiggqlkealldtgaddtvleenslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf

SCOP Domain Coordinates for d1hege_:

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(The format of our PDB-style files is described here.)

Timeline for d1hege_: