SCOPe 2.05: Domain d4kqua_: 4kqu A:

Lineage for d4kqua_ (4kqu A:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.128: Terpenoid synthases [48575] (1 superfamily)
   multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers

4. Superfamily a.128.1: Terpenoid synthases [48576] (6 families)
   duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J

5. Family a.128.1.1: Isoprenyl diphosphate synthases [48577] (4 proteins)

6. Protein automated matches [190489] (5 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187688] (67 PDB entries)

8. Domain d4kqua_: 4kqu A: [266577]
   automated match to d4demf_
   complexed with ahd, ipe, mg; mutant

Details for d4kqua_

PDB Entry: 4kqu, 2.07 Å

PDB Description: Crystal Structure of Farnesyl Synthase Mutant (Y204A) Complexed with Mg, Alendronate and Isopentenyl Pyrophosphate

PDB Compounds: (A:) farnesyl pyrophosphate synthase

SCOPe Domain Sequences for d4kqua_:

Sequence, based on SEQRES records:

>d4kqua_ a.128.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
yaqekqdfvqhfsqivrvltedemghpeigdaiarlkevleynaiggkynrgltvvvafr
elveprkqdadslqrawtvgwcvellqafflvaddimdssltrrgqicwyqkpgvgldai
ndanlleaciyrllklycreqpyylnlielflqssyqteigqtldlltapqgnvdlvrft
ekryksivkyktafasfylpiaaamymagidgekehanakkillemgeffqiqddyldlf
gdpsvtgkigtdiqdnkcswlvvqclqratpeqyqilkenygqkeaekvarvkalyeeld
lpavflqyeedsyshimalieqyaaplppavflglarkiykrrk

Sequence, based on observed residues (ATOM records):

>d4kqua_ a.128.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
yaqekqdfvqhfsqivrvltehpeigdaiarlkevleynaiggkynrgltvvvafrelve
prkqdadslqrawtvgwcvellqafflvaddimdssltrrgqicwyqkpgvgldaindan
lleaciyrllklycreqpyylnlielflqssyqteigqtldlltapqgnvdlvrftekry
ksivkyktafasfylpiaaamymagidgekehanakkillemgeffqiqddyldlfgdps
vtgkigtdiqdnkcswlvvqclqratpeqyqilkenygqkeaekvarvkalyeeldlpav
flqyeedsyshimalieqyaaplppavflglarkiykrrk

Timeline for d4kqua_:

• d4kqua_ is new in SCOPe 2.05-stable
  
• d4kqua_ appears in SCOPe 2.06
  
• d4kqua_ appears in the current release, SCOPe 2.08