SCOPe 2.08: Domain d4kq5a_: 4kq5 A:

Lineage for d4kq5a_ (4kq5 A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.128: Terpenoid synthases [48575] (1 superfamily)
   multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers

4. Superfamily a.128.1: Terpenoid synthases [48576] (6 families)
   duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J

5. Family a.128.1.1: Isoprenyl diphosphate synthases [48577] (4 proteins)

6. Protein automated matches [190489] (5 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187688] (85 PDB entries)

8. Domain d4kq5a_: 4kq5 A: [266575]
   automated match to d4demf_
   complexed with edo, mg, zol; mutant

Details for d4kq5a_

PDB Entry: 4kq5, 2.4 Å

PDB Description: Crystal Structure of Human Farnesyl Pyrophosphate Synthase Mutant (Y204A) Complexed with Mg and Zoledronate

PDB Compounds: (A:) farnesyl pyrophosphate synthase

SCOPe Domain Sequences for d4kq5a_:

Sequence; same for both SEQRES and ATOM records:

>d4kq5a_ a.128.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vyaqekqdfvqhfsqivrvltedemghpeigdaiarlkevleynaiggkynrgltvvvaf
relveprkqdadslqrawtvgwcvellqafflvaddimdssltrrgqicwyqkpgvglda
indanlleaciyrllklycreqpyylnlielflqssyqteigqtldlltapqgnvdlvrf
tekryksivkyktafasfylpiaaamymagidgekehanakkillemgeffqiqddyldl
fgdpsvtgkigtdiqdnkcswlvvqclqratpeqyqilkenygqkeaekvarvkalyeel
dlpavflqyeedsyshimalieqyaaplppavflglarkiyk

Timeline for d4kq5a_:

• d4kq5a_ first appeared in SCOPe 2.05
  
• d4kq5a_ appears in SCOPe 2.07