SCOP 1.61: Domain d1c70a_: 1c70 A:

Lineage for d1c70a_ (1c70 A:)

1. Root: SCOP 1.61

2. Class b: All beta proteins [48724] (111 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)

4. Superfamily b.50.1: Acid proteases [50630] (2 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (7 proteins)

6. Protein Human immunodeficiency virus type 1 protease [50632] (1 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (141 PDB entries)

8. Domain d1c70a_: 1c70 A: [26652]

Details for d1c70a_

PDB Entry: 1c70, 2.5 Å

PDB Description: alternate binding site for the p1-p3 group of a class of potent hiv-1 protease inhibitors as a result of concerted structural change in 80's loop.

SCOP Domain Sequences for d1c70a_:

Sequence; same for both SEQRES and ATOM records:

>d1c70a_ b.50.1.1 (A:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1}
pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf

Timeline for d1c70a_:

• d1c70a_ first appeared (with stable ids) in SCOP 1.55
  
• d1c70a_ appears in SCOP 1.59
  
• d1c70a_ appears in SCOP 1.63
  
• d1c70a_ appears in the current release, SCOPe 2.08