SCOP 1.71: Domain d1qbtb_: 1qbt B:

Lineage for d1qbtb_ (1qbt B:)

1. Root: SCOP 1.71

2. Class b: All beta proteins [48724] (149 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (2 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (8 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (1 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (179 PDB entries)

8. Domain d1qbtb_: 1qbt B: [26632]
   complexed with 146

Details for d1qbtb_

PDB Entry: 1qbt, 2.1 Å

PDB Description: hiv-1 protease inhibitors wiih low nanomolar potency

SCOP Domain Sequences for d1qbtb_:

Sequence; same for both SEQRES and ATOM records:

>d1qbtb_ b.50.1.1 (B:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1}
pqvtlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigatlnf

Timeline for d1qbtb_:

• d1qbtb_ first appeared (with stable ids) in SCOP 1.55
  
• d1qbtb_ appears in SCOP 1.69
  
• d1qbtb_ appears in SCOP 1.73
  
• d1qbtb_ appears in the current release, SCOPe 2.08