SCOPe 2.04: Domain d1a94e_: 1a94 E:

Lineage for d1a94e_ (1a94 E:)

1. Root: SCOPe 2.04

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (8 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (432 PDB entries)
   Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167

8. Domain d1a94e_: 1a94 E: [26602]
   complexed with 0q4

Details for d1a94e_

PDB Entry: 1a94, 2 Å

PDB Description: structural basis for specificity of retroviral proteases

PDB Compounds: (E:) Protease

SCOPe Domain Sequences for d1a94e_:

Sequence; same for both SEQRES and ATOM records:

>d1a94e_ b.50.1.1 (E:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwepkmiggiggfikvrqyd
qiiieiaghkaigtvlvgptpvniigrnlltqigatlnf

Timeline for d1a94e_:

• d1a94e_ first appeared (with stable ids) in SCOP 1.55
  
• d1a94e_ appears in SCOPe 2.03
  
• d1a94e_ appears in SCOPe 2.05
  
• d1a94e_ appears in the current release, SCOPe 2.08