SCOPe 2.07: Domain d1hvhb_: 1hvh B:

Lineage for d1hvhb_ (1hvh B:)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (9 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (578 PDB entries)
   Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167

8. Domain d1hvhb_: 1hvh B: [26586]
   complexed with q82

Details for d1hvhb_

PDB Entry: 1hvh, 1.8 Å

PDB Description: nonpeptide cyclic cyanoguanidines as hiv protease inhibitors

PDB Compounds: (B:) hiv-1 protease

SCOPe Domain Sequences for d1hvhb_:

Sequence; same for both SEQRES and ATOM records:

>d1hvhb_ b.50.1.1 (B:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqvtlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigatlnf

Timeline for d1hvhb_:

• d1hvhb_ first appeared (with stable ids) in SCOP 1.55
  
• d1hvhb_ appears in SCOPe 2.06
  
• d1hvhb_ appears in the current release, SCOPe 2.08