SCOPe 2.05: Domain d3zmza2: 3zmz A:274-654,A:764-836

Lineage for d3zmza2 (3zmz A:274-654,A:764-836)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.3: FAD/NAD(P)-binding domain [51904] (1 superfamily)
   core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander

4. Superfamily c.3.1: FAD/NAD(P)-binding domain [51905] (9 families)

5. Family c.3.1.2: FAD-linked reductases, N-terminal domain [51913] (18 proteins)
   C-terminal domain is alpha+beta is common for the family

6. Protein Lysine-specific histone demethylase 1, LSD1 [159432] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [159433] (27 PDB entries)
   Uniprot O60341 274-654,764-836

8. Domain d3zmza2: 3zmz A:274-654,A:764-836 [265840]
   Other proteins in same PDB: d3zmza1, d3zmza3, d3zmzb1, d3zmzb2
   complexed with fad

Details for d3zmza2

PDB Entry: 3zmz, 3 Å

PDB Description: LSD1-CoREST in complex with PRSFAV peptide

PDB Compounds: (A:) Lysine-specific histone demethylase 1A

SCOPe Domain Sequences for d3zmza2:

Sequence; same for both SEQRES and ATOM records:

>d3zmza2 c.3.1.2 (A:274-654,A:764-836) Lysine-specific histone demethylase 1, LSD1 {Human (Homo sapiens) [TaxId: 9606]}
ptkktgkviiigsgvsglaaarqlqsfgmdvtlleardrvggrvatfrkgnyvadlgamv
vtglggnpmavvskqvnmelakikqkcplyeangqavpkekdemveqefnrlleatsyls
hqldfnvlnnkpvslgqalevviqlqekhvkdeqiehwkkivktqeelkellnkmvnlke
kikelhqqykeasevkpprditaeflvkskhrdltalckeydelaetqgkleeklqelea
nppsdvylssrdrqildwhfanlefanatplstlslkhwdqdddfeftgshltvrngysc
vpvalaegldiklntavrqvrytasgceviavntrstsqtfiykcdavlctlplgvlkqq
ppavqfvpplpewktsavqrmXvaagssgndydlmaqpitpgpsipgapqpiprlffage
htirnypatvhgallsglreagriadqflgamytl

Timeline for d3zmza2:

• d3zmza2 is new in SCOPe 2.05-stable
  
• d3zmza2 appears in SCOPe 2.06
  
• d3zmza2 appears in the current release, SCOPe 2.08