SCOPe 2.08: Domain d3wj4b1: 3wj4 B:207-475

Lineage for d3wj4b1 (3wj4 B:207-475)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48525] (172 PDB entries)
   Uniprot P37231 232-505

8. Domain d3wj4b1: 3wj4 B:207-475 [265664]
   Other proteins in same PDB: d3wj4a2, d3wj4b2
   automated match to d1wm0x_
   protein/DNA complex; complexed with tby

Details for d3wj4b1

PDB Entry: 3wj4, 1.95 Å

PDB Description: Crystal structure of PPARgamma ligand binding domain in complex with tributyltin

PDB Compounds: (B:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d3wj4b1:

Sequence, based on SEQRES records:

>d3wj4b1 a.123.1.1 (B:207-475) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktetdmslhpllqeiykd

Sequence, based on observed residues (ATOM records):

>d3wj4b1 a.123.1.1 (B:207-475) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkkspfviydmnslmmgedkikfkhkev
airifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnkd
gvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsgdr
pgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvik
ktetdhpllqeiykd

Timeline for d3wj4b1:

• d3wj4b1 first appeared in SCOPe 2.05, called d3wj4b_
  
• d3wj4b1 appears in SCOPe 2.07