SCOPe 2.07: Domain d3pt9a3: 3pt9 A:1137-1600

Lineage for d3pt9a3 (3pt9 A:1137-1600)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (60 families)

5. Family c.66.1.26: C5 cytosine-specific DNA methylase, DCM [88786] (5 protein domains)
   automatically mapped to Pfam PF00145

6. Protein Methyltransferase domain from DNA methyltransferase 1 (DNMT1) [267659] (2 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [267737] (4 PDB entries)

8. Domain d3pt9a3: 3pt9 A:1137-1600 [265226]
   Other proteins in same PDB: d3pt9a1, d3pt9a2, d3pt9a4
   automated match to d3ptaa5
   complexed with sah, zn

Details for d3pt9a3

PDB Entry: 3pt9, 2.5 Å

PDB Description: Crystal structure of mouse DNMT1(731-1602) in the free state

PDB Compounds: (A:) DNA (cytosine-5)-methyltransferase 1

SCOPe Domain Sequences for d3pt9a3:

Sequence; same for both SEQRES and ATOM records:

>d3pt9a3 c.66.1.26 (A:1137-1600) Methyltransferase domain from DNA methyltransferase 1 (DNMT1) {Mouse (Mus musculus) [TaxId: 10090]}
iklpklrtldvfsgcgglsegfhqagisetlwaiemwdpaaqafrlnnpgttvftedcnv
llklvmagevtnslgqrlpqkgdvemlcggppcqgfsgmnrfnsrtyskfknslvvsfls
ycdyyrprffllenvrnfvsyrrsmvlkltlrclvrmgyqctfgvlqagqygvaqtrrra
iilaaapgeklplfpeplhvfapracqlsvvvddkkfvsnitrlssgpfrtitvrdtmsd
lpeiqngasnseipyngeplswfqrqlrgshyqpilrdhickdmsplvaarmrhiplfpg
sdwrdlpniqvrlgdgviahklqytfhdvkngysstgalrgvcscaegkacdpesrqfst
lipwclphtgnrhnhwaglygrlewdgffsttvtnpepmgkqgrvlhpeqhrvvsvreca
rsqgfpdsyrffgnildrhrqvgnavppplakaigleiklclls

Timeline for d3pt9a3:

• d3pt9a3 first appeared in SCOPe 2.05
  
• d3pt9a3 appears in SCOPe 2.06