SCOP 1.63: Domain d1hvlb_: 1hvl B:

Lineage for d1hvlb_ (1hvl B:)

1. Root: SCOP 1.63

2. Class b: All beta proteins [48724] (119 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (2 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (8 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (1 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (151 PDB entries)

8. Domain d1hvlb_: 1hvl B: [26520]
   complexed with a76

Details for d1hvlb_

PDB Entry: 1hvl, 1.8 Å

PDB Description: influence of stereochemistry on activity and binding modes for c2 symmetry-based diol inhibitors of hiv-1 protease

SCOP Domain Sequences for d1hvlb_:

Sequence; same for both SEQRES and ATOM records:

>d1hvlb_ b.50.1.1 (B:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1}
pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf

Timeline for d1hvlb_:

• d1hvlb_ first appeared (with stable ids) in SCOP 1.55
  
• d1hvlb_ appears in SCOP 1.61
  
• d1hvlb_ appears in SCOP 1.65
  
• d1hvlb_ appears in the current release, SCOPe 2.08