SCOP 1.69: Domain d1hvka_: 1hvk A:

Lineage for d1hvka_ (1hvk A:)

1. Root: SCOP 1.69

2. Class b: All beta proteins [48724] (144 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (2 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (8 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (1 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (166 PDB entries)

8. Domain d1hvka_: 1hvk A: [26513]

Details for d1hvka_

PDB Entry: 1hvk, 1.8 Å

PDB Description: influence of stereochemistry on activity and binding modes for c2 symmetry-based diol inhibitors of hiv-1 protease

SCOP Domain Sequences for d1hvka_:

Sequence; same for both SEQRES and ATOM records:

>d1hvka_ b.50.1.1 (A:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1}
pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf

Timeline for d1hvka_:

• d1hvka_ first appeared (with stable ids) in SCOP 1.55
  
• d1hvka_ appears in SCOP 1.67
  
• d1hvka_ appears in SCOP 1.71
  
• d1hvka_ appears in the current release, SCOPe 2.08