SCOPe 2.08: Domain d2xrfb_: 2xrf B:

Lineage for d2xrfb_ (2xrf B:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.56: Phosphorylase/hydrolase-like [53162] (8 superfamilies)
   core: 3 layers, a/b/a ; mixed sheet of 5 strands: order 21354; strand 4 is antiparallel to the rest; contains crossover loops

4. Superfamily c.56.2: Purine and uridine phosphorylases [53167] (2 families)
   complex architecture; contains mixed beta-sheet of 8 strands, order 23415867, strands 3, 6 & 7 are antiparallel to the rest; and barrel, closed; n=5, S=8

5. Family c.56.2.0: automated matches [191488] (1 protein)
   not a true family

6. Protein automated matches [190781] (46 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [267813] (6 PDB entries)

8. Domain d2xrfb_: 2xrf B: [264599]
   automated match to d4r31e_
   complexed with gol, mg, ura

Details for d2xrfb_

PDB Entry: 2xrf, 2.3 Å

PDB Description: Crystal structure of human uridine phosphorylase 2

PDB Compounds: (B:) uridine phosphorylase 2

SCOPe Domain Sequences for d2xrfb_:

Sequence, based on SEQRES records:

>d2xrfb_ c.56.2.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rfvhvknpyldlmdedilyhldlgtkthnlpamfgdvkfvcvggspnrmkafalfmhkel
gfeeaeedikdicagtdrycmyktgpvlaishgmgipsisimlhelikllhharccdvti
irigtsggigiapgtvvitdiavdsffkprfeqvildnivtrsteldkelseelfncske
ipnfptlvghtmctydfyegqgrldgalcsfsrekkldylkrafkagvrniemestvfaa
mcglcglkaavvcvtlldrldcdqinlphdvlveyqqrpqllisnfirrrlgl

Sequence, based on observed residues (ATOM records):

>d2xrfb_ c.56.2.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rfvhvknpyldlmdedilyhldlgtkthnlpamfgdvkfvcvggspnrmkafalfmhkel
gfeikdicagtdrycmyktgpvlaishgmgipsisimlhelikllhharccdvtiirigt
sggigiapgtvvitdiavdsffkprfeqvildnivtrsteldkelseelfncskeipnfp
tlvghtmctydfyegqgrldgalcsfsrekkldylkrafkagvrniemestvfaamcglc
glkaavvcvtlldrldcdqinlphdvlveyqqrpqllisnfirrrlgl

Timeline for d2xrfb_:

• d2xrfb_ first appeared in SCOPe 2.05
  
• d2xrfb_ appears in SCOPe 2.07