Lineage for d2xasa1 (2xas A:171-273)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1981147Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (14 superfamilies)
    core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down
  4. 1981148Superfamily a.4.1: Homeodomain-like [46689] (20 families) (S)
    consists only of helices
  5. 1981972Family a.4.1.18: SWIRM domain [140222] (4 protein domains)
    Pfam PF04433; contains extra N-terminal helix
  6. 1981973Protein Lysine-specific histone demethylase 1, LSD1 [140227] (1 species)
  7. 1981974Species Human (Homo sapiens) [TaxId:9606] [140228] (28 PDB entries)
    Uniprot O60341 169-279
  8. 1981992Domain d2xasa1: 2xas A:171-273 [264587]
    Other proteins in same PDB: d2xasa2, d2xasa3, d2xasb1, d2xasb2
    complexed with fad, m80

Details for d2xasa1

PDB Entry: 2xas (more details), 3.2 Å

PDB Description: crystal structure of lsd1-corest in complex with a tranylcypromine derivative (mc2580, 14e)
PDB Compounds: (A:) Lysine-specific histone demethylase 1

SCOPe Domain Sequences for d2xasa1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2xasa1 a.4.1.18 (A:171-273) Lysine-specific histone demethylase 1, LSD1 {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d2xasa1:

Click to download the PDB-style file with coordinates for d2xasa1.
(The format of our PDB-style files is described here.)

Timeline for d2xasa1: