Lineage for d1a1r.1 (1a1r A:,C:)

  1. Root: SCOPe 2.08
  2. Class b: All beta proteins [48724] (180 folds)
  3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. Family b.47.1.3: Viral proteases [50596] (5 proteins)
    beta sheet in the first domain is opened rather than forms a barrel
  6. Protein NS3 protease [50600] (5 species)
  7. Species Human hepatitis C virus (HCV), different isolates [TaxId:11103] [50601] (14 PDB entries)
    Uniprot P27958 1027-1206,1678-1669
    Uniprot P26662 1029-1202,1677-1689
    Uniprot O36579 1054-1207
  8. Domain d1a1r.1: 1a1r A:,C: [26406]
    complexed with zn

Details for d1a1r.1

PDB Entry: 1a1r (more details), 2.5 Å

PDB Description: hcv ns3 protease domain:ns4a peptide complex
PDB Compounds: (A:) ns3 protein, (C:) ns4a protein

SCOPe Domain Sequences for d1a1r.1:

Sequence; same for both SEQRES and ATOM records: (download)

>g1a1r.1 b.47.1.3 (A:,C:) NS3 protease {Human hepatitis C virus (HCV), different isolates [TaxId: 11103]}

SCOPe Domain Coordinates for d1a1r.1 are not available.

Timeline for d1a1r.1:

Domains from other chains:
(mouse over for more information)
d1a1r.2, d1a1r.2, d1a1r.2, d1a1r.2