Lineage for d4r18s_ (4r18 S:)

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1934404Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
    4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing
  4. 1934405Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families) (S)
    N-terminal residue provides two catalytic groups, nucleophile and proton donor
  5. 1934574Family d.153.1.4: Proteasome subunits [56251] (4 proteins)
  6. 1934686Protein Proteasome alpha subunit (non-catalytic) [56255] (7 species)
    contains an extension to the common fold at the N-terminus
  7. 1934702Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56257] (76 PDB entries)
    The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)
  8. 1934771Domain d4r18s_: 4r18 S: [263800]
    Other proteins in same PDB: d4r18a_, d4r18b_, d4r18c_, d4r18d_, d4r18f_, d4r18h_, d4r18i_, d4r18j_, d4r18k_, d4r18l_, d4r18m_, d4r18n_, d4r18o_, d4r18p_, d4r18q_, d4r18r_, d4r18t_, d4r18v_, d4r18w_, d4r18x_, d4r18y_, d4r18z_
    automated match to d4g4sf_
    complexed with aba, mg

Details for d4r18s_

PDB Entry: 4r18 (more details), 2.4 Å

PDB Description: Ligand-induced Lys33-Thr1 crosslinking at subunit beta5 of the yeast 20S proteasome
PDB Compounds: (S:) Proteasome subunit alpha type-6

SCOPe Domain Sequences for d4r18s_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4r18s_ d.153.1.4 (S:) Proteasome alpha subunit (non-catalytic) {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
nnydgdtvtfsptgrlfqveyaleaikqgsvtvglrsnthavlvalkrnadelssyqkki
ikcdehmglslaglapdarvlsnylrqqcnysslvfnrklaveraghllcdkaqkntqsy
ggrpygvglliigydksgahllefqpsgnvtelygtaigarsqgaktylertldtfikid
gnpdelikagveaisqslrdesltvdnlsiaivgkdtpftiydgeavakyi

SCOPe Domain Coordinates for d4r18s_:

Click to download the PDB-style file with coordinates for d4r18s_.
(The format of our PDB-style files is described here.)

Timeline for d4r18s_: