SCOPe 2.08: Domain d4phmb_: 4phm B:

Lineage for d4phmb_ (4phm B:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.39: EF Hand-like [47472] (4 superfamilies)
   core: 4 helices; array of 2 hairpins, opened

4. Superfamily a.39.1: EF-hand [47473] (12 families)
   Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop

5. Family a.39.1.8: Penta-EF-hand proteins [63550] (7 proteins)

6. Protein Calpain small (regulatory) subunit (domain VI) [47552] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [47553] (10 PDB entries)

8. Domain d4phmb_: 4phm B: [263483]
   automated match to d1kfxs_
   complexed with 2ud, ca

Details for d4phmb_

PDB Entry: 4phm, 2.03 Å

PDB Description: the structural basis of differential inhibition of human calpain by indole and phenyl alpha-mercaptoacrylic acids

PDB Compounds: (B:) Calpain small subunit 1

SCOPe Domain Sequences for d4phmb_:

Sequence; same for both SEQRES and ATOM records:

>d4phmb_ a.39.1.8 (B:) Calpain small (regulatory) subunit (domain VI) {Human (Homo sapiens) [TaxId: 9606]}
eevrqfrrlfaqlagddmevsatelmnilnkvvtrhpdlktdgfgidtcrsmvavmdsdt
tgklgfeefkylwnnikrwqaiykqfdtdrsgticsselpgafeaagfhlnehlynmiir
rysdesgnmdfdnfisclvrldamfrafksldkdgtgqiqvniqewlqltmys

Timeline for d4phmb_:

• d4phmb_ first appeared in SCOPe 2.05
  
• d4phmb_ appears in SCOPe 2.07