SCOP 1.73: Domain d1xkbd_: 1xkb D:

Lineage for d1xkbd_ (1xkb D:)

1. Root: SCOP 1.73

2. Class b: All beta proteins [48724] (165 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (47 proteins)

6. Protein Coagulation factor Xa, protease domain [50574] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50575] (58 PDB entries)

8. Domain d1xkbd_: 1xkb D: [26343]
   Other proteins in same PDB: d1xkba1, d1xkba2, d1xkbb1, d1xkbb2
   complexed with 4pp, ca, doh

Details for d1xkbd_

PDB Entry: 1xkb, 2.4 Å

PDB Description: factor xa complexed with a synthetic inhibitor fx-2212a,(2s)-(3'-amidino-3-biphenylyl)-5-(4-pyridylamino)pentanoic acid

PDB Compounds: (D:) blood coagulation factor xa

SCOP Domain Sequences for d1xkbd_:

Sequence; same for both SEQRES and ATOM records:

>d1xkbd_ b.47.1.2 (D:) Coagulation factor Xa, protease domain {Human (Homo sapiens) [TaxId: 9606]}
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt

Timeline for d1xkbd_:

• d1xkbd_ first appeared (with stable ids) in SCOP 1.55
  
• d1xkbd_ appears in SCOP 1.71
  
• d1xkbd_ appears in SCOP 1.75
  
• d1xkbd_ appears in the current release, SCOPe 2.08