SCOP 1.75: Domain d1hcga_: 1hcg A:

Lineage for d1hcga_ (1hcg A:)

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (47 proteins)

6. Protein Coagulation factor Xa, protease domain [50574] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50575] (75 PDB entries)
   Uniprot P00742 235-467

8. Domain d1hcga_: 1hcg A: [26341]
   Other proteins in same PDB: d1hcgb_

Details for d1hcga_

PDB Entry: 1hcg, 2.2 Å

PDB Description: structure of human des(1-45) factor xa at 2.2 angstroms resolution

PDB Compounds: (A:) blood coagulation factor xa

SCOP Domain Sequences for d1hcga_:

Sequence, based on SEQRES records:

>d1hcga_ b.47.1.2 (A:) Coagulation factor Xa, protease domain {Human (Homo sapiens) [TaxId: 9606]}
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktrglpka
k

Sequence, based on observed residues (ATOM records):

>d1hcga_ b.47.1.2 (A:) Coagulation factor Xa, protease domain {Human (Homo sapiens) [TaxId: 9606]}
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqedacqgds
ggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktrglpkak

Timeline for d1hcga_:

• d1hcga_ first appeared (with stable ids) in SCOP 1.55
  
• d1hcga_ appears in SCOP 1.73
  
• d1hcga_ appears in SCOPe 2.01
  
• d1hcga_ appears in the current release, SCOPe 2.08