Lineage for d4ov6b_ (4ov6 B:)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2873305Fold c.41: Subtilisin-like [52742] (1 superfamily)
    3 layers: a/b/a, parallel beta-sheet of 7 strands, order 2314567; left-handed crossover connection between strands 2 & 3
  4. 2873306Superfamily c.41.1: Subtilisin-like [52743] (3 families) (S)
  5. 2873307Family c.41.1.1: Subtilases [52744] (15 proteins)
  6. 2873345Protein Proprotein convertase subtilisin/kexin type 9 [419231] (1 species)
  7. 2873346Species Human (Homo sapiens) [TaxId:9606] [419292] (20 PDB entries)
  8. 2873366Domain d4ov6b_: 4ov6 B: [263353]
    Other proteins in same PDB: d4ov6f_, d4ov6g_
    automated match to d2w2na_
    complexed with edo, pg4

Details for d4ov6b_

PDB Entry: 4ov6 (more details), 2.69 Å

PDB Description: crystal structure of pcsk9(53-451) with adnectin
PDB Compounds: (B:) Proprotein convertase subtilisin/kexin type 9

SCOPe Domain Sequences for d4ov6b_:

Sequence, based on SEQRES records: (download)

>d4ov6b_ c.41.1.1 (B:) Proprotein convertase subtilisin/kexin type 9 {Human (Homo sapiens) [TaxId: 9606]}
sipwnleritppryradeyqppdggslvevylldtsiqsdhreiegrvmvtdfenvpeed
gtrfhrqaskcdshgthlagvvsgrdagvakgasmrslrvlncqgkgtvsgtliglefir
ksqlvqpvgplvvllplaggysrvlnaacqrlaragvvlvtaagnfrddaclyspasape
vitvgatnaqdqpvtlgtlgtnfgrcvdlfapgediigassdcstcfvsqsgtsqaaahv
agiaammlsaepeltlaelrqrlihfsakdvineawfpedqrvltpnlvaalpp

Sequence, based on observed residues (ATOM records): (download)

>d4ov6b_ c.41.1.1 (B:) Proprotein convertase subtilisin/kexin type 9 {Human (Homo sapiens) [TaxId: 9606]}
sipwnleritppslvevylldtsiqsdhreiegrvmvtdfenvpeedgtrfhrqaskcds
hgthlagvvsgrdagvakgasmrslrvlncqgkgtvsgtliglefirksqlvqpvgplvv
llplaggysrvlnaacqrlaragvvlvtaagnfrddaclyspasapevitvgatnaqdqp
vtlgtlgtnfgrcvdlfapgediigassdcstcfvsqsgtsqaaahvagiaammlsaepe
ltlaelrqrlihfsakdvineawfpedqrvltpnlvaalpp

SCOPe Domain Coordinates for d4ov6b_:

Click to download the PDB-style file with coordinates for d4ov6b_.
(The format of our PDB-style files is described here.)

Timeline for d4ov6b_: